Articular cartilage restoration of the knee.

Save the Meniscus, A Good Strategy to Preserve the Knee

With increasing life expectancy, the demand for preservation of native articular cartilage is increasing to delay joint arthroplasties. In the knee, there are many different strategies to preserve the articular cartilage including but not limited to corrective osteotomies, chondral injury restoration, intraarticular injection of cells or growth factors(PRP). However, One of the most important s...

Knee Articular Cartilage Restoration Procedures

Cartilage restoration: overview of treatment options.

In 1743, Hunter11 described ulcerations of articular cartilage as problems that will not heal. The clinical consequences of articular cartilage knee defects are pain, swelling, mechanical symptoms, athletic and functional disability, and osteoarthritis (Figure 1). Full-thickness articular cartilage defects have a poor capacity to heal. The challenge to restore the articular cartilage surface is...

Experimental Study on Protective Role of NSAID on Articular Cartilage Destruction in Septic Arthritis

Background: Surgical drainage and antibiotic therapy are the cornerstones of treatment protocols in septic arthritis; however, in some circumstances, the diagnosis and initiation of treatment may be retarded by slow disease progression or the time when the patient’s condition precludes early surgery. Therefore, it is beneficial to find ways to reduce the amount of articular injury. This study a...

Conditioned medium derived from mesenchymal Stem cells regenerates’ defected articular cartilage

Background & Aims: One of cell- based technical issues associated with cartilage repair assay is delivering cells to the site of the parts where damage is created. Mesenchymal stem cells (MSCs) with their chondrogenic potential are ideal candidates for cartilage regeneration. High expression of cartilage hypertrophy markers by MSCs would result in apoptosis and ossification. This investigation ...

Focal Articular Cartilage Defects of the Knee: Current Review

Injuries to the articular cartilage of the knee are common, they have a significant role in degenerative joint diseases, cartilage is unable to regenerate due to its inherent lack of vascular supply. The management of symptomatic focal traumatic articular cartilage lesions of the knee in active individuals remains a substantial challenge. Although many treatment options are currently available,...